AEP3 | GeneID:856102 | Saccharomyces cerevisiae

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 856102 Official Symbol AEP3
Locus YPL005W Gene Type protein-coding
Synonyms
Full Name N/A
Description Aep3p
Chromosome N/A
Also Known As Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 40489

ID Symbol Protein Species
GeneID:856102 AEP3 NP_015320.1 Saccharomyces cerevisiae
GeneID:2894896 KLLA0F27115g XP_456286.1 Kluyveromyces lactis
GeneID:4622958 AGOS_AGL007W NP_986659.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005737 Component cytoplasm
GO:0019898 Component extrinsic to membrane
GO:0016020 Component membrane
GO:0005743 Component mitochondrial inner membrane
GO:0005739 Component mitochondrion
GO:0003674 Function molecular_function
GO:0006914 Process autophagy
GO:0006112 Process energy reserve metabolic process
GO:0016071 Process mRNA metabolic process

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

Gene Interactions

[ - ] BioGRID Gene Product Interaction Database

Symbol Interaction Binary Experiment Source
APQ12 APQ12 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
ARC1 ARC1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
BRR1 BRR1 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
CAF40 CAF40 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
CDC73 CDC73 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
DEG1 DEG1 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
EAF3 EAF3 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
GCD14 GCD14 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
HSC82 HSC82 / AEP3 Synthetic Growth Defect McClellan AJ (2007)
HSP82 HSP82 / AEP3 Synthetic Growth Defect McClellan AJ (2007)
IFM1 IFM1 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
IKI1 IKI1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
KAP95 KAP95 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
LRP1 LRP1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
LSM7 LSM7 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
MOT2 MOT2 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
MRM1 MRM1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
MRM2 AEP3 / MRM2 Phenotypic Enhancement Wilmes GM (2008)
MSF1 MSF1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
MSK1 MSK1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
MSM1 MSM1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
MSU1 MSU1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
MUD2 MUD2 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
NPL3 NPL3 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
NRP1 NRP1 / AEP3 Phenotypic Suppression Wilmes GM (2008)
PET309 PET309 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
PKH1 PKH1 / AEP3 Affinity Capture-MS Krogan NJ (2006)
PUF2 PUF2 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
REX2 REX2 / AEP3 Phenotypic Suppression Wilmes GM (2008)
RPA49 RPA49 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
RPS8A AEP3 / RPS8A Phenotypic Suppression Wilmes GM (2008)
SAP30 SAP30 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
SUI2 AEP3 / SUI2 Phenotypic Enhancement Wilmes GM (2008)
TAH1 AEP3 / TAH1 Phenotypic Suppression Wilmes GM (2008)
TIF2 TIF2 / AEP3 Phenotypic Suppression Wilmes GM (2008)
TIF3 TIF3 / AEP3 Phenotypic Enhancement Wilmes GM (2008)
TUF1 TUF1 / AEP3 Phenotypic Suppression Wilmes GM (2008)

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Huttenhower C, et al. (2008) "Assessing the functional structure of genomic data." Bioinformatics. 24(13):i330-i338. PMID:18586732
  2. [ + ] McClellan AJ, et al. (2007) "Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches." Cell. 131(1):121-135. PMID:17923092
  3. [ + ] Krogan NJ, et al. (2006) "Global landscape of protein complexes in the yeast Saccharomyces cerevisiae." Nature. 440(7084):637-643. PMID:16554755
  4. [ + ] Ellis TP, et al. (2004) "Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae." J Biol Chem. 279(16):15728-15733. PMID:14742425
  5. [ + ] Huh WK, et al. (2003) "Global analysis of protein localization in budding yeast." Nature. 425(6959):686-691. PMID:14562095
  6. [ + ] Kumar A, et al. (2002) "Subcellular localization of the yeast proteome." Genes Dev. 16(6):707-719. PMID:11914276
  7. [ + ] Bussey H, et al. (1997) "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Nature. 387(6632 Suppl):103-105. PMID:9169875
  8. [ + ] Goffeau A, et al. (1996) "Life with 6000 genes." Science. 274(5287):546, 563-546, 567. PMID:8849441