ABZ2 | GeneID:855333 | Saccharomyces cerevisiae

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 855333 Official Symbol ABZ2
Locus YMR289W Gene Type protein-coding
Synonyms
Full Name N/A
Description Abz2p
Chromosome N/A
Also Known As Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 40011

ID Symbol Protein Species
GeneID:855333 ABZ2 NP_014016.1 Saccharomyces cerevisiae
GeneID:2896321 KLLA0A09603g XP_451419.1 Kluyveromyces lactis
GeneID:4623299 AGOS_AGR330W NP_986996.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005737 Component cytoplasm
GO:0008696 Function 4-amino-4-deoxychorismate lyase activity
GO:0003824 Function catalytic activity
GO:0016829 Function lyase activity
GO:0046656 Process folic acid biosynthetic process
GO:0008152 Process metabolic process
GO:0018193 Process peptidyl-amino acid modification

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

NP_014016   Q03266   S54596  

Gene Interactions

[ - ] BioGRID Gene Product Interaction Database

Symbol Interaction Binary Experiment Source
ABZ2 ABZ2 / ABZ2 Reconstituted Complex Botet J (2007)
N/A N/A / ABZ2 Affinity Capture-MS Krogan NJ (2006)

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Huttenhower C, et al. (2008) "Assessing the functional structure of genomic data." Bioinformatics. 24(13):i330-i338. PMID:18586732
  2. [ + ] Botet J, et al. (2007) "A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase." Eukaryot Cell. 6(11):2102-2111. PMID:17873082
  3. [ + ] Krogan NJ, et al. (2006) "Global landscape of protein complexes in the yeast Saccharomyces cerevisiae." Nature. 440(7084):637-643. PMID:16554755
  4. [ + ] Huh WK, et al. (2003) "Global analysis of protein localization in budding yeast." Nature. 425(6959):686-691. PMID:14562095
  5. [ + ] Bowman S, et al. (1997) "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Nature. 387(6632 Suppl):90-93. PMID:9169872
  6. [ + ] Goffeau A, et al. (1996) "Life with 6000 genes." Science. 274(5287):546, 563-546, 567. PMID:8849441