ABP140 | GeneID:854414 | Saccharomyces cerevisiae

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 854414 Official Symbol ABP140
Locus YOR239W Gene Type protein-coding
Synonyms YOR240W
Full Name N/A
Description Abp140p
Chromosome N/A
Also Known As Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 10174

ID Symbol Protein Species
GeneID:38197 metl NP_728647.2 Drosophila melanogaster
GeneID:52686 Mettl2 NP_766155.2 Mus musculus
GeneID:55798 METTL2B NP_060866.2 Homo sapiens
GeneID:363687 Mettl2 XP_343973.3 Rattus norvegicus
GeneID:480485 METTL2B XP_537604.2 Canis lupus familiaris
GeneID:506221 METTL2B NP_001068714.1 Bos taurus
GeneID:740181 METTL2B XP_001152439.1 Pan troglodytes
GeneID:854414 ABP140 NP_014882.2 Saccharomyces cerevisiae
GeneID:1276647 AgaP_AGAP005973 XP_316017.2 Anopheles gambiae
GeneID:2540321 SPBC21C3.07c NP_596587.1 Schizosaccharomyces pombe
GeneID:2705833 NCU04647.1 XP_324003.1 Neurospora crassa
GeneID:2895088 KLLA0F11385g XP_455598.1 Kluyveromyces lactis
GeneID:4363033 Y53F4B.42 NP_001040827.1 Caenorhabditis elegans
GeneID:4619664 AGOS_ACR130W NP_983532.1 Eremothecium gossypii
GeneID:5050323 MGG_13398 XP_001409331.1 Magnaporthe grisea
GeneID:100006618 mettl2a NP_001017902.1 Danio rerio

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005884 Component actin filament
GO:0005737 Component cytoplasm
GO:0005856 Component cytoskeleton
GO:0043332 Component mating projection tip
GO:0003779 Function actin binding
GO:0051015 Function actin filament binding
GO:0008168 Function methyltransferase activity
GO:0030674 Function protein binding, bridging
GO:0008757 Function S-adenosylmethionine-dependent methyltransferase activity
GO:0016740 Function transferase activity
GO:0030036 Process actin cytoskeleton organization
GO:0006417 Process regulation of translation

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

NP_014882   Q08641  

Gene Interactions

[ - ] BioGRID Gene Product Interaction Database

Symbol Interaction Binary Experiment Source
AKL1 AKL1 / ABP140 Biochemical Activity Ptacek J (2005)
ATG1 ATG1 / ABP140 Biochemical Activity Ptacek J (2005)
BNR1 BNR1 / ABP140 Dosage Rescue Gao L (2008)
HSC82 HSC82 / ABP140 Synthetic Growth Defect McClellan AJ (2007)
HSL1 HSL1 / ABP140 Biochemical Activity Ptacek J (2005)
HSP82 HSP82 / ABP140 Synthetic Growth Defect McClellan AJ (2007)
IME2 IME2 / ABP140 Biochemical Activity Ptacek J (2005)
N/A N/A / ABP140 Biochemical Activity Ptacek J (2005)
SKY1 SKY1 / ABP140 Biochemical Activity Ptacek J (2005)
SWE1 SWE1 / ABP140 Biochemical Activity Ptacek J (2005)
TPK1 TPK1 / ABP140 Biochemical Activity Ptacek J (2005)
YCK1 YCK1 / ABP140 Biochemical Activity Ptacek J (2005)
YCK2 YCK2 / ABP140 Biochemical Activity Ptacek J (2005)

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Huttenhower C, et al. (2008) "Assessing the functional structure of genomic data." Bioinformatics. 24(13):i330-i338. PMID:18586732
  2. [ + ] Gao L, et al. (2008) "Analysis of unregulated formin activity reveals how yeast can balance F-actin assembly between different microfilament-based organizations." Mol Biol Cell. 19(4):1474-1484. PMID:18234843
  3. [ + ] McClellan AJ, et al. (2007) "Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches." Cell. 131(1):121-135. PMID:17923092
  4. [ + ] Ptacek J, et al. (2005) "Global analysis of protein phosphorylation in yeast." Nature. 438(7068):679-684. PMID:16319894
  5. [ + ] Katz JE, et al. (2003) "Automated identification of putative methyltransferases from genomic open reading frames." Mol Cell Proteomics. 2(8):525-540. PMID:12872006
  6. [ + ] Asakura T, et al. (1998) "Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae." Oncogene. 16(1):121-130. PMID:9467951
  7. [ + ] Dujon B, et al. (1997) "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Nature. 387(6632 Suppl):98-102. PMID:9169874
  8. [ + ] Goffeau A, et al. (1996) "Life with 6000 genes." Science. 274(5287):546, 563-546, 567. PMID:8849441