ADO1 | GeneID:853569 | Saccharomyces cerevisiae

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 853569 Official Symbol ADO1
Locus YJR105W Gene Type protein-coding
Synonyms
Full Name N/A
Description Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
Chromosome N/A
Also Known As Ado1p
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 101608

ID Symbol Protein Species
GeneID:853569 ADO1 NP_012639.1 Saccharomyces cerevisiae
GeneID:2539129 SPCC338.14 NP_588154.1 Schizosaccharomyces pombe
GeneID:2684425 MGG_06270 XP_369755.1 Magnaporthe grisea
GeneID:2703994 NCU00414.1 XP_322500.1 Neurospora crassa
GeneID:2893214 KLLA0D10890g XP_453547.1 Kluyveromyces lactis
GeneID:4619219 AGOS_ABR161C NP_983109.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005737 Component cytoplasm
GO:0005634 Component nucleus
GO:0004001 Function adenosine kinase activity
GO:0005524 Function ATP binding
GO:0016301 Function kinase activity
GO:0000166 Function nucleotide binding
GO:0016740 Function transferase activity
GO:0006144 Process purine base metabolic process
GO:0006166 Process purine ribonucleoside salvage

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

AAS56408   CAA89635   CAL48158   NP_012639   P47143   S57126  

Gene Interactions

[ - ] BioGRID Gene Product Interaction Database

Symbol Interaction Binary Experiment Source
AUR1 AUR1 / ADO1 Affinity Capture-MS Krogan NJ (2006)
INP52 INP52 / ADO1 Affinity Capture-MS Ho Y (2002)
KSS1 KSS1 / ADO1 Biochemical Activity Ptacek J (2005)
N/A N/A / ADO1 Affinity Capture-MS Krogan NJ (2006)
N/A N/A / ADO1 Biochemical Activity Ptacek J (2005)
PRP6 PRP6 / ADO1 Affinity Capture-MS Ho Y (2002)
RCK1 RCK1 / ADO1 Biochemical Activity Ptacek J (2005)
RPN4 RPN4 / ADO1 Synthetic Growth Defect Pan X (2006)
SIT4 SIT4 / ADO1 Affinity Capture-MS Ho Y (2002)
SPO12 SPO12 / ADO1 Affinity Capture-MS Graumann J (2004)
SWC4 SWC4 / ADO1 Synthetic Lethality Lin YY (2008)

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Krogan NJ, et al. (2006) "Global landscape of protein complexes in the yeast Saccharomyces cerevisiae." Nature. 440(7084):637-643. PMID:16554755
  2. [ + ] Pan X, et al. (2006) "A DNA integrity network in the yeast Saccharomyces cerevisiae." Cell. 124(5):1069-1081. PMID:16487579
  3. [ + ] Ptacek J, et al. (2005) "Global analysis of protein phosphorylation in yeast." Nature. 438(7068):679-684. PMID:16319894
  4. [ + ] Graumann J, et al. (2004) "Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast." Mol Cell Proteomics. 3(3):226-237. PMID:14660704
  5. [ + ] Huh WK, et al. (2003) "Global analysis of protein localization in budding yeast." Nature. 425(6959):686-691. PMID:14562095
  6. [ + ] Ho Y, et al. (2002) "Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry." Nature. 415(6868):180-183. PMID:11805837
  7. [ + ] Lecoq K, et al. (2001) "Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes." Yeast. 18(4):335-342. PMID:11223943
  8. [ + ] Galibert F, et al. (1996) "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." EMBO J. 15(9):2031-2049. PMID:8641269
  9. [ + ] Goffeau A, et al. (1996) "Life with 6000 genes." Science. 274(5287):546, 563-546, 567. PMID:8849441