ADA2 | GeneID:852059 | Saccharomyces cerevisiae

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 852059 Official Symbol ADA2
Locus YDR448W Gene Type protein-coding
Synonyms SWI8
Full Name N/A
Description Ada2p
Chromosome N/A
Also Known As Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 38834

ID Symbol Protein Species
GeneID:6871 TADA2L NP_001479.3 Homo sapiens
GeneID:217031 Tada2l NP_766150.1 Mus musculus
GeneID:326128 Rpb4 NP_001014636.1 Drosophila melanogaster
GeneID:360581 Tada2l NP_001012141.1 Rattus norvegicus
GeneID:417656 TADA2L NP_001012825.1 Gallus gallus
GeneID:454605 TADA2L XP_001173478.1 Pan troglodytes
GeneID:480596 TADA2L XP_853578.1 Canis lupus familiaris
GeneID:505401 TADA2L NP_001029416.1 Bos taurus
GeneID:797303 zgc:154057 NP_001070609.1 Danio rerio
GeneID:827336 ADA2B NP_974561.1 Arabidopsis thaliana
GeneID:852059 ADA2 NP_010736.1 Saccharomyces cerevisiae
GeneID:2539174 SPCC24B10.08c NP_588011.1 Schizosaccharomyces pombe
GeneID:2675430 MGG_05099 XP_359678.1 Magnaporthe grisea
GeneID:2705714 NCU04459.1 XP_323812.1 Neurospora crassa
GeneID:2897004 KLLA0B01496g XP_451597.1 Kluyveromyces lactis
GeneID:4334126 Os03g0750800 NP_001051287.1 Oryza sativa
GeneID:4621387 AGOS_AER318C NP_985174.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005671 Component Ada2/Gcn5/Ada3 transcription activator complex
GO:0016591 Component DNA-directed RNA polymerase II, holoenzyme
GO:0005634 Component nucleus
GO:0000124 Component SAGA complex
GO:0046695 Component SLIK (SAGA-like) complex
GO:0005669 Component transcription factor TFIID complex
GO:0003677 Function DNA binding
GO:0016251 Function general RNA polymerase II transcription factor activity
GO:0046872 Function metal ion binding
GO:0003702 Function RNA polymerase II transcription factor activity
GO:0016455 Function RNA polymerase II transcription mediator activity
GO:0003713 Function transcription coactivator activity
GO:0008270 Function zinc ion binding
GO:0016568 Process chromatin modification
GO:0016573 Process histone acetylation
GO:0000278 Process mitotic cell cycle
GO:0006473 Process protein amino acid acetylation
GO:0006355 Process regulation of transcription, DNA-dependent
GO:0006357 Process regulation of transcription from RNA polymerase II promoter
GO:0006350 Process transcription
GO:0006366 Process transcription from RNA polymerase II promoter
GO:0006352 Process transcription initiation

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

A43252   AAA34393   AAB64871   NP_010736   Q02336  

Gene Interactions

[ - ] BioGRID Gene Product Interaction Database

Symbol Interaction Binary Experiment Source
ACS2 ACS2 / ADA2 Synthetic Lethality Lin YY (2008)
ADA2 ADA2 / ADA2 Affinity Capture-MS Lee KK (2005)
ADR1 ADR1 / ADA2 Affinity Capture-Western Chiang YC (1996)
AHC1 AHC1 / ADA2 Co-purification Eberharter A (1999)
AHC1 ADA2 / AHC1 Reconstituted Complex Eberharter A (1999)
AHC2 ADA2 / AHC2 Affinity Capture-MS Krogan NJ (2006)
ARP4 ADA2 / ARP4 Synthetic Growth Defect Lin YY (2008)
ARP4 ARP4 / ADA2 Synthetic Growth Defect Lin YY (2008)
BDF1 ADA2 / BDF1 Synthetic Lethality Lin YY (2008)
BEM4 ADA2 / BEM4 Synthetic Growth Defect Lin YY (2008)
BRE1 ADA2 / BRE1 Synthetic Growth Defect Lin YY (2008)
BUR2 ADA2 / BUR2 Synthetic Lethality Lin YY (2008)
CCR4 ADA2 / CCR4 Synthetic Growth Defect Maillet L (2000)
CDC20 ADA2 / CDC20 Synthetic Growth Defect Lin YY (2008)
CDC20 CDC20 / ADA2 Synthetic Growth Defect Lin YY (2008)
CDC31 ADA2 / CDC31 Affinity Capture-MS Rodriguez-Navarro S (2004)
CDC36 ADA2 / CDC36 Affinity Capture-Western Benson JD (1998)
CDH1 ADA2 / CDH1 Synthetic Growth Defect Lin YY (2008)
CHD1 CHD1 / ADA2 Affinity Capture-MS Pray-Grant MG (2005)
CLA4 ADA2 / CLA4 Synthetic Growth Defect Lin YY (2008)
CSE2 ADA2 / CSE2 Synthetic Growth Defect Lin YY (2008)
CTI6 CTI6 / ADA2 Affinity Capture-Western Papamichos-Chronakis M (2002)
DEP1 ADA2 / DEP1 Synthetic Growth Defect Lin YY (2008)
DST1 ADA2 / DST1 Synthetic Lethality Lin YY (2008)
EAF3 ADA2 / EAF3 Synthetic Growth Defect Lin YY (2008)
EAF3 EAF3 / ADA2 Synthetic Growth Defect Lin YY (2008)
EAF5 ADA2 / EAF5 Synthetic Growth Defect Lin YY (2008)
EAF5 EAF5 / ADA2 Synthetic Growth Defect Lin YY (2008)
EAF6 ADA2 / EAF6 Synthetic Growth Defect Lin YY (2008)
EAF6 EAF6 / ADA2 Synthetic Growth Defect Lin YY (2008)
EAF7 ADA2 / EAF7 Synthetic Growth Defect Lin YY (2008)
EAF7 EAF7 / ADA2 Synthetic Growth Defect Lin YY (2008)
ELP2 ADA2 / ELP2 Synthetic Growth Defect Lin YY (2008)
ELP3 ADA2 / ELP3 Synthetic Growth Defect Lin YY (2008)
ELP3 ELP3 / ADA2 Synthetic Growth Defect Lin YY (2008)
ELP4 ADA2 / ELP4 Synthetic Growth Defect Lin YY (2008)
ELP6 ADA2 / ELP6 Synthetic Growth Defect Lin YY (2008)
EPL1 ADA2 / EPL1 Synthetic Lethality Lin YY (2008)
EPL1 EPL1 / ADA2 Synthetic Lethality Lin YY (2008)
ESA1 ADA2 / ESA1 Synthetic Lethality Lin YY (2008)
ESA1 ESA1 / ADA2 Synthetic Lethality Lin YY (2008)
FET3 ADA2 / FET3 Synthetic Growth Defect Lin YY (2008)
FTR1 ADA2 / FTR1 Synthetic Growth Defect Lin YY (2008)
GAL4 GAL4 / ADA2 Affinity Capture-Western Melcher K (1995)
GAL4 GAL4 / ADA2 Reconstituted Complex Carrozza MJ (2002)
GCN4 GCN4 / ADA2 Affinity Capture-Western Drysdale CM (1998)
GCN4 GCN4 / ADA2 Affinity Capture-Western Natarajan K (1998)
GCN4 ADA2 / GCN4 Reconstituted Complex Barlev NA (1995)
GCN4 GCN4 / ADA2 Reconstituted Complex Utley RT (1998)
GCN5 ADA2 / GCN5 Affinity Capture-MS Collins SR (2007)
GCN5 ADA2 / GCN5 Affinity Capture-MS Gavin AC (2006)
GCN5 GCN5 / ADA2 Affinity Capture-MS Graumann J (2004)
GCN5 GCN5 / ADA2 Affinity Capture-MS Ho Y (2002)
GCN5 ADA2 / GCN5 Affinity Capture-MS Kohler A (2008)
GCN5 ADA2 / GCN5 Affinity Capture-MS Krogan NJ (2006)
GCN5 ADA2 / GCN5 Affinity Capture-MS Lee KK (2005)
GCN5 ADA2 / GCN5 Affinity Capture-MS Rodriguez-Navarro S (2004)
GCN5 ADA2 / GCN5 Affinity Capture-Western Candau R (1996)
GCN5 GCN5 / ADA2 Affinity Capture-Western Candau R (1996)
GCN5 ADA2 / GCN5 Affinity Capture-Western Candau R (1996)
GCN5 GCN5 / ADA2 Affinity Capture-Western Candau R (1996)
GCN5 ADA2 / GCN5 Affinity Capture-Western Candau R (1997)
GCN5 GCN5 / ADA2 Affinity Capture-Western Candau R (1997)
GCN5 ADA2 / GCN5 Affinity Capture-Western Henry KW (2003)
GCN5 ADA2 / GCN5 Affinity Capture-Western Horiuchi J (1995)
GCN5 ADA2 / GCN5 Affinity Capture-Western Marcus GA (1994)
GCN5 ADA2 / GCN5 Affinity Capture-Western Qiu H (2005)
GCN5 ADA2 / GCN5 Affinity Capture-Western Sterner DE (2002)
GCN5 ADA2 / GCN5 Co-purification Boyer LA (2002)
GCN5 ADA2 / GCN5 Co-purification Henry KW (2003)
GCN5 ADA2 / GCN5 Co-purification Horiuchi J (1997)
GCN5 ADA2 / GCN5 Reconstituted Complex Balasubramanian R (2002)
GCN5 ADA2 / GCN5 Reconstituted Complex Candau R (1996)
GCN5 ADA2 / GCN5 Reconstituted Complex Eberharter A (1999)
GCN5 GCN5 / ADA2 Synthetic Rescue Chiu YH (2003)
GCN5 ADA2 / GCN5 Two-hybrid Marcus GA (1994)
GCN5 GCN5 / ADA2 Two-hybrid Uetz P (2000)
GCN5 GCN5 / ADA2 Two-hybrid Wang L (1997)
GCN5L2 GCN5L2 / ADA2 Reconstituted Complex Wang L (1997)
GCN5L2 GCN5L2 / ADA2 Two-hybrid Wang L (1997)
GRR1 ADA2 / GRR1 Synthetic Growth Defect Lin YY (2008)
HFI1 ADA2 / HFI1 Affinity Capture-MS Collins SR (2007)
HFI1 ADA2 / HFI1 Affinity Capture-MS Gavin AC (2006)
HFI1 HFI1 / ADA2 Affinity Capture-MS Gavin AC (2006)
HFI1 ADA2 / HFI1 Affinity Capture-MS Kohler A (2008)
HFI1 ADA2 / HFI1 Affinity Capture-MS Krogan NJ (2006)
HFI1 ADA2 / HFI1 Affinity Capture-MS Lee KK (2005)
HFI1 ADA2 / HFI1 Affinity Capture-MS Rodriguez-Navarro S (2004)
HFI1 HFI1 / ADA2 Affinity Capture-MS Sermwittayawong D (2006)
HFI1 ADA2 / HFI1 Affinity Capture-Western Horiuchi J (1997)
HFI1 ADA2 / HFI1 Affinity Capture-Western Sterner DE (2002)
HFI1 ADA2 / HFI1 Co-purification Horiuchi J (1997)
HFI1 ADA2 / HFI1 Synthetic Growth Defect Lin YY (2008)
HHT1 ADA2 / HHT1 Affinity Capture-MS Rodriguez-Navarro S (2004)
HHT1 ADA2 / HHT1 Synthetic Growth Defect Lin YY (2008)
HOG1 ADA2 / HOG1 Affinity Capture-Western Zapater M (2007)
HTA1 ADA2 / HTA1 Affinity Capture-MS Rodriguez-Navarro S (2004)
HTA1 HTA1 / ADA2 Co-purification Grant PA (1999)
HTB1 ADA2 / HTB1 Phenotypic Suppression Mutiu AI (2007)
HTZ1 ADA2 / HTZ1 Synthetic Growth Defect Lin YY (2008)
HTZ1 HTZ1 / ADA2 Synthetic Growth Defect Santisteban MS (2000)
IES3 ADA2 / IES3 Synthetic Lethality Lin YY (2008)
IKI3 ADA2 / IKI3 Synthetic Growth Defect Lin YY (2008)
IPP1 ADA2 / IPP1 Synthetic Growth Defect Lin YY (2008)
IRE1 IRE1 / ADA2 Reconstituted Complex Welihinda AA (2000)
ISW1 ADA2 / ISW1 Synthetic Growth Defect Lin YY (2008)
ISW2 ADA2 / ISW2 Synthetic Growth Defect Lin YY (2008)
IXR1 ADA2 / IXR1 Synthetic Growth Defect Lin YY (2008)
LGE1 ADA2 / LGE1 Synthetic Growth Defect Lin YY (2008)
MED1 ADA2 / MED1 Affinity Capture-MS Collins SR (2007)
MED1 MED1 / ADA2 Affinity Capture-MS Gavin AC (2006)
MED1 ADA2 / MED1 Synthetic Lethality Lin YY (2008)
MED2 ADA2 / MED2 Synthetic Lethality Lin YY (2008)
MED6 ADA2 / MED6 Affinity Capture-MS Collins SR (2007)
MED7 ADA2 / MED7 Affinity Capture-MS Collins SR (2007)
MED7 MED7 / ADA2 Affinity Capture-MS Gavin AC (2002)
MED7 MED7 / ADA2 Affinity Capture-MS Gavin AC (2006)
MOT2 ADA2 / MOT2 Synthetic Growth Defect Maillet L (2000)
MYO4 ADA2 / MYO4 Co-localization Cosma MP (1999)
N/A ADA2 / N/A Synthetic Growth Defect Lin YY (2008)
NGG1 NGG1 / ADA2 Affinity Capture-MS Collins SR (2007)
NGG1 ADA2 / NGG1 Affinity Capture-MS Gavin AC (2006)
NGG1 ADA2 / NGG1 Affinity Capture-MS Kohler A (2006)
NGG1 ADA2 / NGG1 Affinity Capture-MS Kohler A (2008)
NGG1 NGG1 / ADA2 Affinity Capture-MS Krogan NJ (2006)
NGG1 ADA2 / NGG1 Affinity Capture-MS Lee KK (2005)
NGG1 ADA2 / NGG1 Affinity Capture-MS Rodriguez-Navarro S (2004)
NGG1 ADA2 / NGG1 Affinity Capture-Western Candau R (1996)
NGG1 NGG1 / ADA2 Affinity Capture-Western Candau R (1996)
NGG1 ADA2 / NGG1 Affinity Capture-Western Candau R (1996)
NGG1 NGG1 / ADA2 Affinity Capture-Western Candau R (1996)
NGG1 ADA2 / NGG1 Affinity Capture-Western Henry KW (2003)
NGG1 ADA2 / NGG1 Affinity Capture-Western Horiuchi J (1995)
NGG1 NGG1 / ADA2 Affinity Capture-Western Horiuchi J (1995)
NGG1 NGG1 / ADA2 Affinity Capture-Western Natarajan K (1998)
NGG1 ADA2 / NGG1 Affinity Capture-Western Saleh A (1997)
NGG1 NGG1 / ADA2 Affinity Capture-Western Saleh A (1997)
NGG1 ADA2 / NGG1 Affinity Capture-Western Saleh A (1998)
NGG1 NGG1 / ADA2 Affinity Capture-Western Saleh A (1998)
NGG1 ADA2 / NGG1 Co-fractionation Saleh A (1997)
NGG1 ADA2 / NGG1 Co-purification Boyer LA (2002)
NGG1 ADA2 / NGG1 Co-purification Horiuchi J (1997)
NGG1 NGG1 / ADA2 Reconstituted Complex Balasubramanian R (2002)
NGG1 ADA2 / NGG1 Reconstituted Complex Candau R (1996)
NGG1 ADA2 / NGG1 Reconstituted Complex Eberharter A (1999)
NGG1 ADA2 / NGG1 Two-hybrid Benecke A (2002)
NGG1 NGG1 / ADA2 Two-hybrid Ito T (2001)
NOT5 ADA2 / NOT5 Synthetic Growth Defect Maillet L (2000)
NTO1 ADA2 / NTO1 Synthetic Growth Defect Lin YY (2008)
NUT1 ADA2 / NUT1 Affinity Capture-MS Collins SR (2007)
NUT1 ADA2 / NUT1 Synthetic Growth Defect Lin YY (2008)
NUT1 NUT1 / ADA2 Synthetic Growth Defect Lin YY (2008)
PAF1 ADA2 / PAF1 Synthetic Lethality Lin YY (2008)
PCF11 PCF11 / ADA2 Two-hybrid Uetz P (2000)
PEX32 ADA2 / PEX32 Synthetic Growth Defect Lin YY (2008)
PHO2 ADA2 / PHO2 Synthetic Growth Defect Lin YY (2008)
PHO23 ADA2 / PHO23 Synthetic Growth Defect Lin YY (2008)
PHO23 PHO23 / ADA2 Synthetic Growth Defect Lin YY (2008)
PKR1 ADA2 / PKR1 Synthetic Growth Defect Lin YY (2008)
PRE9 ADA2 / PRE9 Synthetic Lethality Lin YY (2008)
RAD6 ADA2 / RAD6 Synthetic Growth Defect Lin YY (2008)
RIC1 ADA2 / RIC1 Synthetic Growth Defect Lin YY (2008)
RPB9 RPB9 / ADA2 Synthetic Lethality Van Mullem V (2002)
RPD3 ADA2 / RPD3 Synthetic Growth Defect Lin YY (2008)
RPD3 RPD3 / ADA2 Synthetic Growth Defect Lin YY (2008)
RSC2 ADA2 / RSC2 Synthetic Growth Defect Lin YY (2008)
RTT109 ADA2 / RTT109 Synthetic Growth Defect Lin YY (2008)
RTT109 RTT109 / ADA2 Synthetic Growth Defect Lin YY (2008)
SAC3 ADA2 / SAC3 Affinity Capture-MS Rodriguez-Navarro S (2004)
SAC3 ADA2 / SAC3 Affinity Capture-Western Kohler A (2008)
SAP30 ADA2 / SAP30 Synthetic Growth Defect Lin YY (2008)
SAP30 SAP30 / ADA2 Synthetic Growth Defect Lin YY (2008)
SAS3 ADA2 / SAS3 Synthetic Growth Defect Lin YY (2008)
SAS3 SAS3 / ADA2 Synthetic Growth Defect Lin YY (2008)
SDS3 ADA2 / SDS3 Synthetic Growth Defect Lin YY (2008)
SGF11 SGF11 / ADA2 Affinity Capture-MS Ingvarsdottir K (2005)
SGF11 SGF11 / ADA2 Affinity Capture-MS Krogan NJ (2006)
SGF11 ADA2 / SGF11 Affinity Capture-MS Lee KK (2004)
SGF11 SGF11 / ADA2 Affinity Capture-MS Lee KK (2004)
SGF11 ADA2 / SGF11 Affinity Capture-MS Lee KK (2005)
SGF11 SGF11 / ADA2 Affinity Capture-MS Lee KK (2005)
SGF11 SGF11 / ADA2 Affinity Capture-MS Powell DW (2004)
SGF11 ADA2 / SGF11 Synthetic Growth Defect Lin YY (2008)
SGF29 SGF29 / ADA2 Affinity Capture-MS Collins SR (2007)
SGF29 ADA2 / SGF29 Affinity Capture-MS Gavin AC (2006)
SGF29 SGF29 / ADA2 Affinity Capture-MS Gavin AC (2006)
SGF29 ADA2 / SGF29 Affinity Capture-MS Kohler A (2008)
SGF29 SGF29 / ADA2 Affinity Capture-MS Krogan NJ (2006)
SGF29 ADA2 / SGF29 Affinity Capture-MS Lee KK (2005)
SGF29 ADA2 / SGF29 Affinity Capture-MS Rodriguez-Navarro S (2004)
SGF29 SGF29 / ADA2 Affinity Capture-MS Sanders SL (2002)
SGF73 ADA2 / SGF73 Affinity Capture-MS Collins SR (2007)
SGF73 ADA2 / SGF73 Affinity Capture-MS Gavin AC (2006)
SGF73 SGF73 / ADA2 Affinity Capture-MS Gavin AC (2006)
SGF73 ADA2 / SGF73 Affinity Capture-MS Kohler A (2008)
SGF73 ADA2 / SGF73 Affinity Capture-MS Lee KK (2005)
SGF73 ADA2 / SGF73 Affinity Capture-MS Rodriguez-Navarro S (2004)
SGF73 SGF73 / ADA2 Affinity Capture-MS Sanders SL (2002)
SGF73 ADA2 / SGF73 Affinity Capture-Western Kohler A (2008)
SGF73 ADA2 / SGF73 Synthetic Growth Defect Lin YY (2008)
SIN3 ADA2 / SIN3 Synthetic Growth Defect Lin YY (2008)
SIN3 SIN3 / ADA2 Synthetic Growth Defect Lin YY (2008)
SIN4 ADA2 / SIN4 Affinity Capture-MS Collins SR (2007)
SIN4 ADA2 / SIN4 Synthetic Growth Defect Lin YY (2008)
SNF2 ADA2 / SNF2 Co-localization Cosma MP (1999)
SNF2 ADA2 / SNF2 Synthetic Growth Defect Sterner DE (1999)
SNT1 ADA2 / SNT1 Synthetic Growth Defect Lin YY (2008)
SOH1 ADA2 / SOH1 Synthetic Growth Defect Lin YY (2008)
SPC25 SPC25 / ADA2 Two-hybrid Wong J (2007)
SPT15 SPT15 / ADA2 Affinity Capture-MS Sanders SL (2002)
SPT15 SPT15 / ADA2 Affinity Capture-Western Barlev NA (1995)
SPT2 ADA2 / SPT2 Synthetic Rescue Pollard KJ (1997)
SPT20 ADA2 / SPT20 Affinity Capture-MS Collins SR (2007)
SPT20 ADA2 / SPT20 Affinity Capture-MS Gavin AC (2006)
SPT20 SPT20 / ADA2 Affinity Capture-MS Gavin AC (2006)
SPT20 ADA2 / SPT20 Affinity Capture-MS Kohler A (2008)
SPT20 ADA2 / SPT20 Affinity Capture-MS Krogan NJ (2006)
SPT20 ADA2 / SPT20 Affinity Capture-MS Lee KK (2005)
SPT20 ADA2 / SPT20 Affinity Capture-MS Rodriguez-Navarro S (2004)
SPT20 ADA2 / SPT20 Affinity Capture-Western Henry KW (2003)
SPT20 ADA2 / SPT20 Affinity Capture-Western Sterner DE (2002)
SPT20 ADA2 / SPT20 Co-localization Cosma MP (1999)
SPT20 ADA2 / SPT20 Co-purification Boyer LA (2002)
SPT20 ADA2 / SPT20 Co-purification Horiuchi J (1997)
SPT20 ADA2 / SPT20 Reconstituted Complex Belotserkovskaya R (2000)
SPT20 ADA2 / SPT20 Synthetic Growth Defect Lin YY (2008)
SPT3 SPT3 / ADA2 Affinity Capture-MS Collins SR (2007)
SPT3 ADA2 / SPT3 Affinity Capture-MS Gavin AC (2006)
SPT3 ADA2 / SPT3 Affinity Capture-MS Kohler A (2008)
SPT3 SPT3 / ADA2 Affinity Capture-MS Krogan NJ (2006)
SPT3 ADA2 / SPT3 Affinity Capture-MS Lee KK (2005)
SPT3 ADA2 / SPT3 Affinity Capture-MS Rodriguez-Navarro S (2004)
SPT3 ADA2 / SPT3 Affinity Capture-Western Sterner DE (2002)
SPT3 ADA2 / SPT3 Co-purification Boyer LA (2002)
SPT3 ADA2 / SPT3 Co-purification Henry KW (2003)
SPT3 ADA2 / SPT3 Reconstituted Complex Belotserkovskaya R (2000)
SPT3 ADA2 / SPT3 Synthetic Growth Defect Lin YY (2008)
SPT7 SPT7 / ADA2 Affinity Capture-MS Collins SR (2007)
SPT7 SPT7 / ADA2 Affinity Capture-MS Gavin AC (2002)
SPT7 ADA2 / SPT7 Affinity Capture-MS Gavin AC (2006)
SPT7 SPT7 / ADA2 Affinity Capture-MS Gavin AC (2006)
SPT7 ADA2 / SPT7 Affinity Capture-MS Kohler A (2006)
SPT7 ADA2 / SPT7 Affinity Capture-MS Kohler A (2008)
SPT7 ADA2 / SPT7 Affinity Capture-MS Krogan NJ (2006)
SPT7 ADA2 / SPT7 Affinity Capture-MS Lee KK (2005)
SPT7 ADA2 / SPT7 Affinity Capture-MS Rodriguez-Navarro S (2004)
SPT7 SPT7 / ADA2 Affinity Capture-MS Wu PY (2004)
SPT7 ADA2 / SPT7 Affinity Capture-Western Hoke SM (2007)
SPT7 ADA2 / SPT7 Affinity Capture-Western Qiu H (2005)
SPT7 ADA2 / SPT7 Affinity Capture-Western Saleh A (1998)
SPT7 ADA2 / SPT7 Affinity Capture-Western Sterner DE (2002)
SPT7 SPT7 / ADA2 Affinity Capture-Western Wu PY (2002)
SPT7 SPT7 / ADA2 Co-purification Pray-Grant MG (2002)
SPT7 ADA2 / SPT7 Synthetic Growth Defect Lin YY (2008)
SPT8 ADA2 / SPT8 Affinity Capture-MS Collins SR (2007)
SPT8 ADA2 / SPT8 Affinity Capture-MS Gavin AC (2006)
SPT8 SPT8 / ADA2 Affinity Capture-MS Gavin AC (2006)
SPT8 ADA2 / SPT8 Affinity Capture-MS Kohler A (2008)
SPT8 ADA2 / SPT8 Affinity Capture-MS Lee KK (2005)
SPT8 ADA2 / SPT8 Affinity Capture-MS Rodriguez-Navarro S (2004)
SPT8 ADA2 / SPT8 Affinity Capture-Western Sterner DE (2002)
SPT8 ADA2 / SPT8 Co-purification Henry KW (2003)
SPT8 SPT8 / ADA2 Co-purification Sterner DE (1999)
SPT8 ADA2 / SPT8 Reconstituted Complex Belotserkovskaya R (2000)
SPT8 SPT8 / ADA2 Reconstituted Complex Eberharter A (1999)
SPT8 ADA2 / SPT8 Synthetic Growth Defect Lin YY (2008)
SPT8 SPT8 / ADA2 Synthetic Growth Defect Lin YY (2008)
SRB2 ADA2 / SRB2 Affinity Capture-MS Collins SR (2007)
SRB2 ADA2 / SRB2 Synthetic Growth Defect Sterner DE (1999)
SRB5 ADA2 / SRB5 Synthetic Growth Defect Sterner DE (1999)
SRB6 SRB6 / ADA2 Affinity Capture-MS Collins SR (2007)
SRB6 SRB6 / ADA2 Affinity Capture-MS Gavin AC (2002)
SRB6 SRB6 / ADA2 Affinity Capture-MS Gavin AC (2006)
SSN2 ADA2 / SSN2 Synthetic Growth Defect Lin YY (2008)
SSN3 ADA2 / SSN3 Synthetic Growth Defect Lin YY (2008)
SSN8 ADA2 / SSN8 Synthetic Growth Defect Lin YY (2008)
STE14 ADA2 / STE14 Synthetic Growth Defect Lin YY (2008)
STE50 ADA2 / STE50 Synthetic Growth Defect Lin YY (2008)
SUS1 ADA2 / SUS1 Affinity Capture-MS Rodriguez-Navarro S (2004)
SUS1 SUS1 / ADA2 Affinity Capture-MS Rodriguez-Navarro S (2004)
SUS1 ADA2 / SUS1 Affinity Capture-Western Kohler A (2008)
SWC4 ADA2 / SWC4 Synthetic Growth Defect Lin YY (2008)
SWC4 SWC4 / ADA2 Synthetic Growth Defect Lin YY (2008)
SWD1 ADA2 / SWD1 Synthetic Growth Defect Lin YY (2008)
SWD3 ADA2 / SWD3 Synthetic Growth Defect Lin YY (2008)
SWI1 ADA2 / SWI1 Synthetic Growth Defect Sterner DE (1999)
SWI1 ADA2 / SWI1 Synthetic Lethality Pollard KJ (1997)
SWI4 ADA2 / SWI4 Synthetic Growth Defect Lin YY (2008)
SWI5 ADA2 / SWI5 Co-localization Cosma MP (1999)
SWI6 ADA2 / SWI6 Synthetic Growth Defect Lin YY (2008)
Tada3l ADA2 / Tada3l Two-hybrid Benecke A (2002)
TAF1 ADA2 / TAF1 Affinity Capture-MS Collins SR (2007)
TAF1 TAF1 / ADA2 Affinity Capture-MS Gavin AC (2002)
TAF1 TAF1 / ADA2 Affinity Capture-MS Gavin AC (2006)
TAF1 ADA2 / TAF1 Reconstituted Complex Belotserkovskaya R (2000)
TAF10 TAF10 / ADA2 Affinity Capture-MS Collins SR (2007)
TAF10 TAF10 / ADA2 Affinity Capture-MS Gavin AC (2002)
TAF10 TAF10 / ADA2 Affinity Capture-MS Gavin AC (2006)
TAF10 ADA2 / TAF10 Affinity Capture-MS Kohler A (2008)
TAF10 TAF10 / ADA2 Affinity Capture-MS Krogan NJ (2006)
TAF10 ADA2 / TAF10 Affinity Capture-MS Lee KK (2005)
TAF10 ADA2 / TAF10 Affinity Capture-MS Rodriguez-Navarro S (2004)
TAF10 TAF10 / ADA2 Affinity Capture-MS Sanders SL (2002)
TAF10 TAF10 / ADA2 Affinity Capture-Western Kirchner J (2001)
TAF10 TAF10 / ADA2 Affinity Capture-Western Kirschner DB (2002)
TAF10 TAF10 / ADA2 Co-purification Pray-Grant MG (2002)
TAF11 ADA2 / TAF11 Affinity Capture-MS Collins SR (2007)
TAF12 TAF12 / ADA2 Affinity Capture-MS Collins SR (2007)
TAF12 ADA2 / TAF12 Affinity Capture-MS Gavin AC (2006)
TAF12 ADA2 / TAF12 Affinity Capture-MS Kohler A (2006)
TAF12 ADA2 / TAF12 Affinity Capture-MS Kohler A (2008)
TAF12 ADA2 / TAF12 Affinity Capture-MS Krogan NJ (2006)
TAF12 ADA2 / TAF12 Affinity Capture-MS Lee KK (2005)
TAF12 ADA2 / TAF12 Affinity Capture-MS Rodriguez-Navarro S (2004)
TAF12 TAF12 / ADA2 Affinity Capture-MS Sanders SL (2002)
TAF12 ADA2 / TAF12 Affinity Capture-Western Qiu H (2005)
TAF12 ADA2 / TAF12 Co-purification Boyer LA (2002)
TAF12 ADA2 / TAF12 Reconstituted Complex Belotserkovskaya R (2000)
TAF3 ADA2 / TAF3 Affinity Capture-MS Collins SR (2007)
TAF5 TAF5 / ADA2 Affinity Capture-MS Collins SR (2007)
TAF5 TAF5 / ADA2 Affinity Capture-MS Gavin AC (2002)
TAF5 ADA2 / TAF5 Affinity Capture-MS Gavin AC (2006)
TAF5 TAF5 / ADA2 Affinity Capture-MS Gavin AC (2006)
TAF5 ADA2 / TAF5 Affinity Capture-MS Kohler A (2008)
TAF5 ADA2 / TAF5 Affinity Capture-MS Lee KK (2005)
TAF5 ADA2 / TAF5 Affinity Capture-MS Rodriguez-Navarro S (2004)
TAF5 TAF5 / ADA2 Affinity Capture-MS Sanders SL (2002)
TAF5 TAF5 / ADA2 Affinity Capture-Western Drysdale CM (1998)
TAF5 TAF5 / ADA2 Affinity Capture-Western Natarajan K (1998)
TAF5 ADA2 / TAF5 Affinity Capture-Western Sterner DE (2002)
TAF5 TAF5 / ADA2 Affinity Capture-Western Takahata S (2004)
TAF5 TAF5 / ADA2 Co-purification Grant PA (1998)
TAF6 ADA2 / TAF6 Affinity Capture-MS Collins SR (2007)
TAF6 TAF6 / ADA2 Affinity Capture-MS Gavin AC (2002)
TAF6 ADA2 / TAF6 Affinity Capture-MS Gavin AC (2006)
TAF6 TAF6 / ADA2 Affinity Capture-MS Gavin AC (2006)
TAF6 TAF6 / ADA2 Affinity Capture-MS Ingvarsdottir K (2005)
TAF6 ADA2 / TAF6 Affinity Capture-MS Kohler A (2008)
TAF6 ADA2 / TAF6 Affinity Capture-MS Krogan NJ (2006)
TAF6 ADA2 / TAF6 Affinity Capture-MS Lee KK (2005)
TAF6 ADA2 / TAF6 Affinity Capture-MS Rodriguez-Navarro S (2004)
TAF6 TAF6 / ADA2 Affinity Capture-MS Sanders SL (2002)
TAF6 ADA2 / TAF6 Affinity Capture-Western Henry KW (2003)
TAF6 ADA2 / TAF6 Affinity Capture-Western Sterner DE (2002)
TAF6 TAF6 / ADA2 Co-purification Sterner DE (2002)
TAF6 ADA2 / TAF6 Reconstituted Complex Belotserkovskaya R (2000)
TAF9 ADA2 / TAF9 Affinity Capture-MS Collins SR (2007)
TAF9 ADA2 / TAF9 Affinity Capture-MS Gavin AC (2006)
TAF9 TAF9 / ADA2 Affinity Capture-MS Gavin AC (2006)
TAF9 ADA2 / TAF9 Affinity Capture-MS Lee KK (2005)
TAF9 ADA2 / TAF9 Affinity Capture-MS Rodriguez-Navarro S (2004)
TAF9 ADA2 / TAF9 Affinity Capture-Western Qiu H (2005)
TAF9 TAF9 / ADA2 Co-purification Grant PA (1998)
TAF9 TAF9 / ADA2 Synthetic Lethality Milgrom E (2005)
TFP1 ADA2 / TFP1 Synthetic Growth Defect Lin YY (2008)
THP1 ADA2 / THP1 Affinity Capture-MS Rodriguez-Navarro S (2004)
THP1 ADA2 / THP1 Affinity Capture-Western Kohler A (2008)
TRA1 ADA2 / TRA1 Affinity Capture-MS Collins SR (2007)
TRA1 ADA2 / TRA1 Affinity Capture-MS Gavin AC (2006)
TRA1 ADA2 / TRA1 Affinity Capture-MS Kohler A (2006)
TRA1 ADA2 / TRA1 Affinity Capture-MS Kohler A (2008)
TRA1 ADA2 / TRA1 Affinity Capture-MS Lee KK (2005)
TRA1 ADA2 / TRA1 Affinity Capture-MS Rodriguez-Navarro S (2004)
TRA1 ADA2 / TRA1 Affinity Capture-Western Saleh A (1998)
TRA1 TRA1 / ADA2 Affinity Capture-Western Saleh A (1998)
TRA1 ADA2 / TRA1 Affinity Capture-Western Sterner DE (2002)
UBP8 ADA2 / UBP8 Affinity Capture-MS Collins SR (2007)
UBP8 ADA2 / UBP8 Affinity Capture-MS Kohler A (2006)
UBP8 ADA2 / UBP8 Affinity Capture-MS Kohler A (2008)
UBP8 UBP8 / ADA2 Affinity Capture-MS Krogan NJ (2006)
UBP8 ADA2 / UBP8 Affinity Capture-MS Lee KK (2005)
UBP8 UBP8 / ADA2 Affinity Capture-MS Lee KK (2005)
UBP8 ADA2 / UBP8 Affinity Capture-MS Rodriguez-Navarro S (2004)
UBP8 UBP8 / ADA2 Affinity Capture-MS Sanders SL (2002)
UBP8 UBP8 / ADA2 Affinity Capture-Western Daniel JA (2004)
UBP8 ADA2 / UBP8 Affinity Capture-Western Henry KW (2003)
UBP8 ADA2 / UBP8 Affinity Capture-Western Ingvarsdottir K (2005)
UBP8 ADA2 / UBP8 Co-purification Henry KW (2003)
VID21 ADA2 / VID21 Synthetic Growth Defect Lin YY (2008)
VID21 VID21 / ADA2 Synthetic Growth Defect Lin YY (2008)
VMA2 ADA2 / VMA2 Synthetic Growth Defect Lin YY (2008)
VMA22 ADA2 / VMA22 Synthetic Growth Defect Lin YY (2008)
VMA7 ADA2 / VMA7 Synthetic Growth Defect Lin YY (2008)
VMA8 ADA2 / VMA8 Synthetic Growth Defect Lin YY (2008)
VPH2 ADA2 / VPH2 Synthetic Growth Defect Lin YY (2008)
WHI5 ADA2 / WHI5 Synthetic Growth Defect Lin YY (2008)
YAF9 ADA2 / YAF9 Synthetic Growth Defect Lin YY (2008)
YAF9 YAF9 / ADA2 Synthetic Growth Defect Lin YY (2008)
YAP1 ADA2 / YAP1 Affinity Capture-MS Collins SR (2007)
YAP1 YAP1 / ADA2 Affinity Capture-MS Gavin AC (2006)
YNG1 ADA2 / YNG1 Synthetic Growth Defect Lin YY (2008)
YNG2 ADA2 / YNG2 Synthetic Lethality Lin YY (2008)
YNG2 YNG2 / ADA2 Synthetic Lethality Lin YY (2008)
YTA7 ADA2 / YTA7 Synthetic Growth Defect Lin YY (2008)

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Huttenhower C, et al. (2008) "Assessing the functional structure of genomic data." Bioinformatics. 24(13):i330-i338. PMID:18586732
  2. [ + ] Kohler A, et al. (2008) "Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export." Nat Cell Biol. 10(6):707-715. PMID:18488019
  3. [ + ] Tian W, et al. (2008) "Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function." Genome Biol. 9 Suppl 1():S7. PMID:18613951
  4. [ + ] Mutiu AI, et al. (2007) "The role of histone ubiquitylation and deubiquitylation in gene expression as determined by the analysis of an HTB1(K123R) Saccharomyces cerevisiae strain." Mol Genet Genomics. 277(5):491-506. PMID:17447102
  5. [ + ] Collins SR, et al. (2007) "Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae." Mol Cell Proteomics. 6(3):439-450. PMID:17200106
  6. [ + ] Zapater M, et al. (2007) "Selective requirement for SAGA in Hog1-mediated gene expression depending on the severity of the external osmostress conditions." Mol Cell Biol. 27(11):3900-3910. PMID:17403898
  7. [ + ] Hoke SM, et al. (2007) "C-terminal processing of yeast Spt7 occurs in the absence of functional SAGA complex." BMC Biochem. 8():16. PMID:17686179
  8. [ + ] Wong J, et al. (2007) "A protein interaction map of the mitotic spindle." Mol Biol Cell. 18(10):3800-3809. PMID:17634282
  9. [ + ] Ferreiro JA, et al. (2006) "Roles for Gcn5p and Ada2p in transcription and nucleotide excision repair at the Saccharomyces cerevisiae MET16 gene." Nucleic Acids Res. 34(3):976-985. PMID:16473851
  10. [ + ] Sermwittayawong D, et al. (2006) "SAGA binds TBP via its Spt8 subunit in competition with DNA: implications for TBP recruitment." EMBO J. 25(16):3791-3800. PMID:16888622
  11. [ + ] Kohler A, et al. (2006) "The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11." Mol Biol Cell. 17(10):4228-4236. PMID:16855026
  12. [ + ] Krogan NJ, et al. (2006) "Global landscape of protein complexes in the yeast Saccharomyces cerevisiae." Nature. 440(7084):637-643. PMID:16554755
  13. [ + ] Gavin AC, et al. (2006) "Proteome survey reveals modularity of the yeast cell machinery." Nature. 440(7084):631-636. PMID:16429126
  14. [ + ] Ingvarsdottir K, et al. (2005) "H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex." Mol Cell Biol. 25(3):1162-1172. PMID:15657441
  15. [ + ] Milgrom E, et al. (2005) "TFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts allele." Genetics. 171(3):959-973. PMID:16118188
  16. [ + ] Qiu H, et al. (2005) "Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p." Mol Cell Biol. 25(9):3461-3474. PMID:15831453
  17. [ + ] Lee KK, et al. (2005) "The deubiquitylation activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA complex." Mol Cell Biol. 25(3):1173-1182. PMID:15657442
  18. [ + ] Pray-Grant MG, et al. (2005) "Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation." Nature. 433(7024):434-438. PMID:15647753
  19. [ + ] Graumann J, et al. (2004) "Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast." Mol Cell Proteomics. 3(3):226-237. PMID:14660704
  20. [ + ] Lee KK, et al. (2004) "Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits." Biochem Soc Trans. 32(Pt 6):899-903. PMID:15506919
  21. [ + ] Powell DW, et al. (2004) "Cluster analysis of mass spectrometry data reveals a novel component of SAGA." Mol Cell Biol. 24(16):7249-7259. PMID:15282323
  22. [ + ] Wu PY, et al. (2004) "Molecular architecture of the S. cerevisiae SAGA complex." Mol Cell. 15(2):199-208. PMID:15260971
  23. [ + ] Takahata S, et al. (2004) "Autonomous function of the amino-terminal inhibitory domain of TAF1 in transcriptional regulation." Mol Cell Biol. 24(8):3089-3099. PMID:15060133
  24. [ + ] Rodriguez-Navarro S, et al. (2004) "Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery." Cell. 116(1):75-86. PMID:14718168
  25. [ + ] Daniel JA, et al. (2004) "Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription." J Biol Chem. 279(3):1867-1871. PMID:14660634
  26. [ + ] Henry KW, et al. (2003) "Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8." Genes Dev. 17(21):2648-2663. PMID:14563679
  27. [ + ] Chiu YH, et al. (2003) "A targeted histone acetyltransferase can create a sizable region of hyperacetylated chromatin and counteract the propagation of transcriptionally silent chromatin." Genetics. 165(1):115-125. PMID:14504221
  28. [ + ] Boyer LA, et al. (2002) "Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes." Mol Cell. 10(4):935-942. PMID:12419236
  29. [ + ] Balasubramanian R, et al. (2002) "Role of the Ada2 and Ada3 transcriptional coactivators in histone acetylation." J Biol Chem. 277(10):7989-7995. PMID:11773077
  30. [ + ] Sterner DE, et al. (2002) "The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex." J Biol Chem. 277(10):8178-8186. PMID:11777910
  31. [ + ] Van Mullem V, et al. (2002) "The Rpb9 subunit of RNA polymerase II binds transcription factor TFIIE and interferes with the SAGA and elongator histone acetyltransferases." J Biol Chem. 277(12):10220-10225. PMID:11779853
  32. [ + ] Gavin AC, et al. (2002) "Functional organization of the yeast proteome by systematic analysis of protein complexes." Nature. 415(6868):141-147. PMID:11805826
  33. [ + ] Ho Y, et al. (2002) "Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry." Nature. 415(6868):180-183. PMID:11805837
  34. [ + ] Kulesza CA, et al. (2002) "Adenovirus E1A requires the yeast SAGA histone acetyltransferase complex and associates with SAGA components Gcn5 and Tra1." Oncogene. 21(9):1411-1422. PMID:11857084
  35. [ + ] Kirschner DB, et al. (2002) "Distinct mutations in yeast TAF(II)25 differentially affect the composition of TFIID and SAGA complexes as well as global gene expression patterns." Mol Cell Biol. 22(9):3178-3193. PMID:11940675
  36. [ + ] Carrozza MJ, et al. (2002) "Gal80 confers specificity on HAT complex interactions with activators." J Biol Chem. 277(27):24648-24652. PMID:11986320
  37. [ + ] Benecke A, et al. (2002) "ADA3-containing complexes associate with estrogen receptor alpha." Nucleic Acids Res. 30(11):2508-2514. PMID:12034840
  38. [ + ] Sanders SL, et al. (2002) "Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry." Mol Cell Biol. 22(13):4723-4738. PMID:12052880
  39. [ + ] Papamichos-Chronakis M, et al. (2002) "Cti6, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1." Mol Cell. 9(6):1297-1305. PMID:12086626
  40. [ + ] Wu PY, et al. (2002) "Analysis of Spt7 function in the Saccharomyces cerevisiae SAGA coactivator complex." Mol Cell Biol. 22(15):5367-5379. PMID:12101232
  41. [ + ] Sterner DE, et al. (2002) "SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription." Proc Natl Acad Sci U S A. 99(18):11622-11627. PMID:12186975
  42. [ + ] Pray-Grant MG, et al. (2002) "The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway." Mol Cell Biol. 22(24):8774-8786. PMID:12446794
  43. [ + ] Ito T, et al. (2001) "A comprehensive two-hybrid analysis to explore the yeast protein interactome." Proc Natl Acad Sci U S A. 98(8):4569-4574. PMID:11283351
  44. [ + ] Kirchner J, et al. (2001) "Molecular genetic dissection of TAF25, an essential yeast gene encoding a subunit shared by TFIID and SAGA multiprotein transcription factors." Mol Cell Biol. 21(19):6668-6680. PMID:11533254
  45. [ + ] Maillet L, et al. (2000) "The essential function of Not1 lies within the Ccr4-Not complex." J Mol Biol. 303(2):131-143. PMID:11023781
  46. [ + ] Sterner DE, et al. (2000) "Acetylation of histones and transcription-related factors." Microbiol Mol Biol Rev. 64(2):435-459. PMID:10839822
  47. [ + ] Uetz P, et al. (2000) "A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae." Nature. 403(6770):623-627. PMID:10688190
  48. [ + ] Santisteban MS, et al. (2000) "Histone H2A.Z regulats transcription and is partially redundant with nucleosome remodeling complexes." Cell. 103(3):411-422. PMID:11081628
  49. [ + ] Welihinda AA, et al. (2000) "The transcriptional co-activator ADA5 is required for HAC1 mRNA processing in vivo." J Biol Chem. 275(5):3377-3381. PMID:10652329
  50. [ + ] Belotserkovskaya R, et al. (2000) "Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters." Mol Cell Biol. 20(2):634-647. PMID:10611242