ACA2 | GeneID:829918 | Arabidopsis thaliana

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 829918 Official Symbol ACA2
Locus AT4G37640 Gene Type protein-coding
Synonyms CALCIUM ATPASE 2; F19F18.130; F19F18_130
Full Name N/A
Description ACA2 (CALCIUM ATPASE 2); calcium ion transmembrane transporter/ calcium-transporting ATPase/ calmodulin binding
Chromosome N/A
Also Known As
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 56150

ID Symbol Protein Species
GeneID:491 ATP2B2 NP_001001331.1 Homo sapiens
GeneID:11941 Atp2b2 NP_033853.1 Mus musculus
GeneID:24215 Atp2b2 NP_036640.1 Rattus norvegicus
GeneID:415958 ATP2B2 XP_001231642.1 Gallus gallus
GeneID:460168 ATP2B4 XP_001151685.1 Pan troglodytes
GeneID:476535 ATP2B2 XP_861077.1 Canis lupus familiaris
GeneID:557430 atp2b2 XP_001919907.1 Danio rerio
GeneID:613800 ATP2B2 XP_870026.2 Bos taurus
GeneID:816826 AT2G22950 NP_179879.1 Arabidopsis thaliana
GeneID:829918 ACA2 NP_195479.1 Arabidopsis thaliana
GeneID:852878 PMC1 NP_011509.1 Saccharomyces cerevisiae
GeneID:2543477 SPAPB2B4.04c NP_593890.1 Schizosaccharomyces pombe
GeneID:2681584 MGG_02487 XP_365785.2 Magnaporthe grisea
GeneID:2706049 NCU04736.1 XP_324093.1 Neurospora crassa
GeneID:2896403 KLLA0A08910g XP_451391.1 Kluyveromyces lactis
GeneID:4331984 Os03g0203700 NP_001049307.1 Oryza sativa
GeneID:4621774 AGOS_AFL011W NP_985537.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005783 Component endoplasmic reticulum
GO:0005789 Component endoplasmic reticulum membrane
GO:0015085 Function calcium ion transmembrane transporter activity
GO:0005388 Function calcium-transporting ATPase activity
GO:0005516 Function calmodulin binding
GO:0006810 Process transport

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_119927 NP_195479 Q53XI0   O81108  

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]


Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

Transcript Cluster

[ - ] NCBI's UniGene

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Anil VS, et al. (2008) "A plant Ca2+ pump, ACA2, relieves salt hypersensitivity in yeast. Modulation of cytosolic calcium signature and activation of adaptive Na+ homeostasis." J Biol Chem. 283(6):3497-3506. PMID:18073213
  2. [ + ] Dunkley TP, et al. (2006) "Mapping the Arabidopsis organelle proteome." Proc Natl Acad Sci U S A. 103(17):6518-6523. PMID:16618929
  3. [ + ] Baxter I, et al. (2003) "Genomic comparison of P-type ATPase ion pumps in Arabidopsis and rice." Plant Physiol. 132(2):618-628. PMID:12805592
  4. [ + ] Reddy VS, et al. (2002) "Genes encoding calmodulin-binding proteins in the Arabidopsis genome." J Biol Chem. 277(12):9840-9852. PMID:11782485
  5. [ + ] Hwang I, et al. (2000) "A calcium-dependent protein kinase can inhibit a calmodulin-stimulated Ca2+ pump (ACA2) located in the endoplasmic reticulum of Arabidopsis." Proc Natl Acad Sci U S A. 97(11):6224-6229. PMID:10823962
  6. [ + ] Hwang I, et al. (2000) "Calmodulin activation of an endoplasmic reticulum-located calcium pump involves an interaction with the N-terminal autoinhibitory domain." Plant Physiol. 122(1):157-168. PMID:10631259
  7. [ + ] Harper JF, et al. (1998) "A novel calmodulin-regulated Ca2+-ATPase (ACA2) from Arabidopsis with an N-terminal autoinhibitory domain." J Biol Chem. 273(2):1099-1106. PMID:9422775