ABCB4 | GeneID:819314 | Arabidopsis thaliana

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 819314 Official Symbol ABCB4
Locus AT2G47000 Gene Type protein-coding
Synonyms ATP BINDING CASSETTE SUBFAMILY B4; F14M4.17; MDR4; MULTIDRUG RESISTANCE 4; P-GLYCOPROTEIN 4; PGP4
Full Name N/A
Description ABCB4 (ATP BINDING CASSETTE SUBFAMILY B4); ATPase, coupled to transmembrane movement of substances / xenobiotic-transporting ATPase
Chromosome N/A
Also Known As
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 113698

ID Symbol Protein Species
GeneID:5244 ABCB4 NP_061337.1 Homo sapiens
GeneID:18670 Abcb4 NP_032856.1 Mus musculus
GeneID:24891 Abcb4 NP_036822.1 Rattus norvegicus
GeneID:36428 Mdr49 NP_523724.2 Drosophila melanogaster
GeneID:748364 ABCB4 XP_001160982.1 Pan troglodytes
GeneID:819314 MDR4/PGP4 NP_182223.1 Arabidopsis thaliana
GeneID:825388 PGP21 NP_191774.1 Arabidopsis thaliana
GeneID:826951 MDR3/PGP3 NP_192091.1 Arabidopsis thaliana
GeneID:826974 PGP5 NP_192092.1 Arabidopsis thaliana
GeneID:827530 PGP9 NP_193539.2 Arabidopsis thaliana
GeneID:834697 PGP7 NP_199466.1 Arabidopsis thaliana
GeneID:839282 PGP12 NP_171754.1 Arabidopsis thaliana
GeneID:839353 PGP11 NP_171753.1 Arabidopsis thaliana
GeneID:1276325 AgaP_AGAP005639 XP_315658.1 Anopheles gambiae
GeneID:4323895 Os01g0695700 NP_001043962.1 Oryza sativa

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0016020 Component membrane
GO:0005886 Component plasma membrane
GO:0042626 Function ATPase activity, coupled to transmembrane movement of substances
GO:0008559 Function xenobiotic-transporting ATPase activity
GO:0010315 Process auxin efflux
GO:0009926 Process auxin polar transport
GO:0010540 Process basipetal auxin transport
GO:0009630 Process gravitropism
GO:0009733 Process response to auxin stimulus
GO:0009735 Process response to cytokinin stimulus
GO:0048767 Process root hair elongation

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_130268 NP_182223

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

NM_130268  

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

AAC34225   NP_182223   O80725   T02187  

Transcript Cluster

[ - ] NCBI's UniGene

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Lewis DR, et al. (2007) "Separating the roles of acropetal and basipetal auxin transport on gravitropism with mutations in two Arabidopsis multidrug resistance-like ABC transporter genes." Plant Cell. 19(6):1838-1850. PMID:17557805
  2. [ + ] Cho M, et al. (2007) "P-glycoprotein4 displays auxin efflux transporter-like action in Arabidopsis root hair cells and tobacco cells." Plant Cell. 19(12):3930-3943. PMID:18156217
  3. [ + ] Dunkley TP, et al. (2006) "Mapping the Arabidopsis organelle proteome." Proc Natl Acad Sci U S A. 103(17):6518-6523. PMID:16618929
  4. [ + ] Terasaka K, et al. (2005) "PGP4, an ATP binding cassette P-glycoprotein, catalyzes auxin transport in Arabidopsis thaliana roots." Plant Cell. 17(11):2922-2939. PMID:16243904