5-HT7 | GeneID:43669 | Drosophila melanogaster

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 43669 Official Symbol 5-HT7
Locus Dmel_CG12073 Gene Type protein-coding
Synonyms 5-HT-dro; 5-HT-dro1; 5-HT7Dro; 5-HT[[7Dro]]; 5-HT[[7]]; 5-HT[[7]]Dro; 5-HT[[dro1]]; 5-HTdro1; 5HT-R1; 5HT-dro; 5HT-dro1; 5HT[[7Dro]]; 5htdror; CG12073; DRO1; Dm5HTdro1; DmelCG12073
Full Name N/A
Description Serotonin receptor 7
Chromosome 100B1-100B1
Also Known As 5-HT7-PA; CG12073-PA; serotonin receptor; serotonin receptor 1; serotonin receptor 7
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 669

ID Symbol Protein Species
GeneID:3351 HTR1B NP_000854.1 Homo sapiens
GeneID:15551 Htr1b NP_034612.1 Mus musculus
GeneID:25075 Htr1b NP_071561.1 Rattus norvegicus
GeneID:43669 5-HT7 NP_524599.1 Drosophila melanogaster
GeneID:317707 HTR1B XP_583895.2 Bos taurus
GeneID:421858 HTR1B XP_419875.1 Gallus gallus
GeneID:462833 HTR1B NP_001009102.1 Pan troglodytes
GeneID:561647 LOC561647 XP_690153.1 Danio rerio
GeneID:1274062 GPRNNA20 XP_313127.2 Anopheles gambiae
GeneID:1274064 GPR5HT7 XP_313129.1 Anopheles gambiae

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0016021 Component integral to membrane
GO:0005887 Component integral to plasma membrane
GO:0005886 Component plasma membrane
GO:0008227 Function amine receptor activity
GO:0004952 Function dopamine receptor activity
GO:0016609 Function G-protein coupled serotonin receptor activity
GO:0004993 Function serotonin receptor activity
GO:0007192 Process activation of adenylate cyclase activity by serotonin receptor signaling pathway
GO:0007210 Process serotonin receptor signaling pathway

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_079860 NP_524599

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

NM_079860  

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

Transcript Cluster

[ - ] NCBI's UniGene

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Smith CD, et al. (2007) "The Release 5.1 annotation of Drosophila melanogaster heterochromatin." Science. 316(5831):1586-1591. PMID:17569856
  2. [ + ] Hoskins RA, et al. (2007) "Sequence finishing and mapping of Drosophila melanogaster heterochromatin." Science. 316(5831):1625-1628. PMID:17569867
  3. [ + ] Quesneville H, et al. (2005) "Combined evidence annotation of transposable elements in genome sequences." PLoS Comput Biol. 1(2):166-175. PMID:16110336
  4. [ + ] Kearney JB, et al. (2004) "Gene expression profiling of the developing Drosophila CNS midline cells." Dev Biol. 275(2):473-492. PMID:15501232
  5. [ + ] Kerr M, et al. (2004) "Cell-specific manipulation of second messengers; a toolbox for integrative physiology in Drosophila." Curr Biol. 14(16):1468-1474. PMID:15324663
  6. [ + ] Misra S, et al. (2002) "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Genome Biol. 3(12):RESEARCH0083. PMID:12537572
  7. [ + ] Radford JC, et al. (2002) "Systematic G-protein-coupled receptor analysis in Drosophila melanogaster identifies a leucokinin receptor with novel roles." J Biol Chem. 277(41):38810-38817. PMID:12163486
  8. [ + ] Celniker SE, et al. (2002) "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence." Genome Biol. 3(12):RESEARCH0079. PMID:12537568
  9. [ + ] Hoskins RA, et al. (2002) "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly." Genome Biol. 3(12):RESEARCH0085. PMID:12537574
  10. [ + ] Kaminker JS, et al. (2002) "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective." Genome Biol. 3(12):RESEARCH0084. PMID:12537573
  11. [ + ] Blenau W, et al. (2001) "Molecular and pharmacological properties of insect biogenic amine receptors: lessons from Drosophila melanogaster and Apis mellifera." Arch Insect Biochem Physiol. 48(1):13-38. PMID:11519073
  12. [ + ] Ma E, et al. (2001) "Mutation in pre-mRNA adenosine deaminase markedly attenuates neuronal tolerance to O2 deprivation in Drosophila melanogaster." J Clin Invest. 107(6):685-693. PMID:11254668
  13. [ + ] Tierney AJ, et al. (2001) "Structure and function of invertebrate 5-HT receptors: a review." Comp Biochem Physiol A Mol Integr Physiol. 128(4):791-804. PMID:11282322
  14. [ + ] Brody T, et al. (2000) "Drosophila melanogaster G protein-coupled receptors." J Cell Biol. 150(2):F83-F88. PMID:10908591
  15. [ + ] Adams MD, et al. (2000) "The genome sequence of Drosophila melanogaster." Science. 287(5461):2185-2195. PMID:10731132
  16. [ + ] Pebusque MJ, et al. (1998) "Ancient large-scale genome duplications: phylogenetic and linkage analyses shed light on chordate genome evolution." Mol Biol Evol. 15(9):1145-1159. PMID:9729879
  17. [ + ] Han KA, et al. (1998) "A novel octopamine receptor with preferential expression in Drosophila mushroom bodies." J Neurosci. 18(10):3650-3658. PMID:9570796
  18. [ + ] Obosi LA, et al. (1996) "Functional characterisation of the Drosophila 5-HTdro1 and 5-HTdro2B serotonin receptors in insect cells: activation of a G(alpha) s-like protein by 5-HTdro1 but lack of coupling to inhibitory G-proteins by 5-HTdro2B." FEBS Lett. 381(3):233-236. PMID:8601462
  19. [ + ] Feng G, et al. (1996) "Cloning and functional characterization of a novel dopamine receptor from Drosophila melanogaster." J Neurosci. 16(12):3925-3933. PMID:8656286
  20. [ + ] Saudou F, et al. (1992) "A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns." EMBO J. 11(1):7-17. PMID:1310937
  21. [ + ] Witz P, et al. (1990) "Cloning and characterization of a Drosophila serotonin receptor that activates adenylate cyclase." Proc Natl Acad Sci U S A. 87(22):8940-8944. PMID:2174167
  22. [ + ] Saudou F, et al. (1990) "Cloning and characterization of a Drosophila tyramine receptor." EMBO J. 9(11):3611-3617. PMID:2170118