aim1 | GeneID:3361036 | Schizosaccharomyces pombe

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 3361036 Official Symbol aim1
Locus SPCC320.13c Gene Type protein-coding
Synonyms SPCC330.16; ark1
Full Name N/A
Description aurora-B kinase Ark1
Chromosome N/A
Also Known As
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 2670

ID Symbol Protein Species
GeneID:6790 AURKA NP_940835.1 Homo sapiens
GeneID:20878 Aurka NP_035627.1 Mus musculus
GeneID:41446 aur NP_476749.1 Drosophila melanogaster
GeneID:172268 air-2 NP_491714.1 Caenorhabditis elegans
GeneID:261730 Aurka NP_695208.2 Rattus norvegicus
GeneID:428167 AURKA XP_425725.1 Gallus gallus
GeneID:445246 zgc:100912 NP_001003640.1 Danio rerio
GeneID:469980 AURKA XP_525364.2 Pan troglodytes
GeneID:485940 AURKA XP_543064.2 Canis lupus familiaris
GeneID:504437 AURKA NP_001033117.1 Bos taurus
GeneID:819157 ATAUR3 NP_182073.1 Arabidopsis thaliana
GeneID:855892 IPL1 NP_015115.1 Saccharomyces cerevisiae
GeneID:1281324 AgaP_AGAP001793 XP_321274.2 Anopheles gambiae
GeneID:2674701 MGG_00479 XP_368765.1 Magnaporthe grisea
GeneID:2704361 NCU00108.1 XP_322194.1 Neurospora crassa
GeneID:2897422 KLLA0B02332g XP_451635.1 Kluyveromyces lactis
GeneID:3361036 aim1 NP_001018849.1 Schizosaccharomyces pombe
GeneID:4334220 Os03g0765000 NP_001051373.1 Oryza sativa
GeneID:4621676 AGOS_AFL101C NP_985449.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0032133 Component chromosome passenger complex
GO:0000777 Component condensed chromosome kinetochore
GO:0005634 Component nucleus
GO:0051233 Component spindle midzone
GO:0005524 Function ATP binding
GO:0005515 Function protein binding
GO:0004674 Function protein serine/threonine kinase activity
GO:0051315 Process attachment of spindle microtubules to kinetochore during mitosis
GO:0000910 Process cytokinesis
GO:0007094 Process mitotic cell cycle spindle assembly checkpoint
GO:0000070 Process mitotic sister chromatid segregation
GO:0006468 Process protein amino acid phosphorylation
GO:0034501 Process protein localization to kinetochore
GO:0034503 Process protein localization to nucleolar rDNA repeats
GO:0031134 Process sister chromatid biorientation

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_001022711 NP_001018849

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Nakazawa N, et al. (2008) "Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis." J Cell Biol. 180(6):1115-1131. PMID:18362178
  2. [ + ] Hauf S, et al. (2007) "Aurora controls sister kinetochore mono-orientation and homolog bi-orientation in meiosis-I." EMBO J. 26(21):4475-4486. PMID:17932486
  3. [ + ] Gregan J, et al. (2007) "The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation." Curr Biol. 17(14):1190-1200. PMID:17627824
  4. [ + ] Kawashima SA, et al. (2007) "Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres." Genes Dev. 21(4):420-435. PMID:17322402
  5. [ + ] Aslett M, et al. (2006) "Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%." Yeast. 23(13):913-919. PMID:17072883
  6. [ + ] Huang HK, et al. (2005) "Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation." Mol Cell Biol. 25(20):9000-9015. PMID:16199877
  7. [ + ] Trautmann S, et al. (2004) "The S. pombe Cdc14-like phosphatase Clp1p regulates chromosome biorientation and interacts with Aurora kinase." Dev Cell. 7(5):755-762. PMID:15525536
  8. [ + ] Petersen J, et al. (2003) "S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response." Curr Biol. 13(7):590-597. PMID:12676091
  9. [ + ] Leverson JD, et al. (2002) "The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis." Mol Biol Cell. 13(4):1132-1143. PMID:11950927
  10. [ + ] Wood V, et al. (2002) "The genome sequence of Schizosaccharomyces pombe." Nature. 415(6874):871-880. PMID:11859360
  11. [ + ] Petersen J, et al. (2001) "The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation." J Cell Sci. 114(Pt 24):4371-4384. PMID:11792803