alp7 | GeneID:2543382 | Schizosaccharomyces pombe

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 2543382 Official Symbol alp7
Locus SPAC890.02c Gene Type protein-coding
Synonyms mia1
Full Name N/A
Description TACC homolog (predicted) (PMID 14742702)
Chromosome N/A
Also Known As
Summary N/A

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0015630 Component microtubule cytoskeleton
GO:0005816 Component spindle pole body
GO:0005515 Function protein binding
GO:0034613 Process cellular protein localization
GO:0000132 Process establishment of mitotic spindle orientation
GO:0007163 Process establishment or maintenance of cell polarity
GO:0051225 Process spindle assembly
GO:0030953 Process spindle astral microtubule organization

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_001020249 NP_594820

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

CAB63493   NP_594820   Q9URY2   T50258  

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Zheng L, et al. (2007) "The Spindle Pole Bodies Facilitate Nuclear Envelope Division during Closed Mitosis in Fission Yeast." PLoS Biol. 5(7):e170. PMID:17579515
  2. [ + ] Sato M, et al. (2007) "Alp7/TACC is a crucial target in Ran-GTPase-dependent spindle formation in fission yeast." Nature. 447(7142):334-337. PMID:17476213
  3. [ + ] Tafforeau L, et al. (2006) "Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF." EMBO J. 25(19):4547-4556. PMID:17016471
  4. [ + ] Sato M, et al. (2004) "Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation." Mol Biol Cell. 15(4):1609-1622. PMID:14742702
  5. [ + ] Sato M, et al. (2003) "Deletion of Mia1/Alp7 activates Mad2-dependent spindle assembly checkpoint in fission yeast." Nat Cell Biol. 5(9):764-6; author reply 766. PMID:12951601
  6. [ + ] Oliferenko S, et al. (2002) "Astral microtubules monitor metaphase spindle alignment in fission yeast." Nat Cell Biol. 4(10):816-820. PMID:12360293
  7. [ + ] Wood V, et al. (2002) "The genome sequence of Schizosaccharomyces pombe." Nature. 415(6874):871-880. PMID:11859360
  8. [ + ] Radcliffe P, et al. (1998) "Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants." Mol Biol Cell. 9(7):1757-1771. PMID:9658169