act2 | GeneID:2543233 | Schizosaccharomyces pombe

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 2543233 Official Symbol act2
Locus SPAC630.03 Gene Type protein-coding
Synonyms arp3
Full Name N/A
Description actin-like protein Arp3
Chromosome N/A
Also Known As
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 4180

ID Symbol Protein Species
GeneID:57180 ACTR3B NP_065178.1 Homo sapiens
GeneID:242894 Actr3b NP_001004365.1 Mus musculus
GeneID:362298 Actr3b XP_342612.2 Rattus norvegicus
GeneID:420439 ACTR3B XP_418544.1 Gallus gallus
GeneID:475549 ACTR3B XP_532772.2 Canis lupus familiaris
GeneID:616404 ACTR3B XP_873511.2 Bos taurus
GeneID:738748 ACTR3B XP_001144350.1 Pan troglodytes
GeneID:837876 DIS1 NP_172777.1 Arabidopsis thaliana
GeneID:853528 ARP3 NP_012599.1 Saccharomyces cerevisiae
GeneID:2543233 act2 NP_592898.1 Schizosaccharomyces pombe
GeneID:2677366 MGG_03879 XP_361405.2 Magnaporthe grisea
GeneID:2709915 NCU01756.1 XP_328195.1 Neurospora crassa
GeneID:2897025 KLLA0B13904g XP_452150.1 Kluyveromyces lactis
GeneID:4329867 Os02g0596900 NP_001047323.1 Oryza sativa
GeneID:4622239 AGOS_AFR419C NP_985966.1 Eremothecium gossypii
GeneID:100038776 zgc:158823 NP_001083025.1 Danio rerio

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0030479 Component actin cortical patch
GO:0005885 Component Arp2/3 protein complex
GO:0005737 Component cytoplasm
GO:0005829 Component cytosol
GO:0003779 Function actin binding
GO:0005524 Function ATP binding
GO:0005515 Function protein binding
GO:0000147 Process actin cortical patch assembly
GO:0000915 Process cytokinesis, contractile ring formation
GO:0007163 Process establishment or maintenance of cell polarity
GO:0030833 Process regulation of actin filament polymerization

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_001018298 NP_592898

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

3DWL-A   3DWL-B   A41790   CAB52725   NP_592898   P32390  

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Aslett M, et al. (2006) "Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%." Yeast. 23(13):913-919. PMID:17072883
  2. [ + ] Matsuyama A, et al. (2006) "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Nat Biotechnol. 24(7):841-847. PMID:16823372
  3. [ + ] Sirotkin V, et al. (2005) "Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast." J Cell Biol. 170(4):637-648. PMID:16087707
  4. [ + ] Wood V, et al. (2002) "The genome sequence of Schizosaccharomyces pombe." Nature. 415(6874):871-880. PMID:11859360
  5. [ + ] Pelham RJ, et al. (2002) "Actin dynamics in the contractile ring during cytokinesis in fission yeast." Nature. 419(6902):82-86. PMID:12214236
  6. [ + ] Morrell JL, et al. (1999) "A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast." Mol Biol Cell. 10(12):4201-4215. PMID:10588653
  7. [ + ] Feoktistova A, et al. (1999) "Identification and characterization of Schizosaccharomyces pombe asp1(+), a gene that interacts with mutations in the Arp2/3 complex and actin." Genetics. 152(3):895-908. PMID:10388810
  8. [ + ] McCollum D, et al. (1996) "The Schizosaccharomyces pombe actin-related protein, Arp3, is a component of the cortical actin cytoskeleton and interacts with profilin." EMBO J. 15(23):6438-6446. PMID:8978671
  9. [ + ] Balasubramanian MK, et al. (1996) "Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin function." EMBO J. 15(23):6426-6437. PMID:8978670