aff1 | GeneID:2540258 | Schizosaccharomyces pombe

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 2540258 Official Symbol aff1
Locus SPBC32C12.02 Gene Type protein-coding
Synonyms ste11; stex
Full Name N/A
Description transcription factor Ste11
Chromosome N/A
Also Known As
Summary N/A

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005829 Component cytosol
GO:0005634 Component nucleus
GO:0034064 Component Tor2-Mei2-Ste11 complex
GO:0003700 Function transcription factor activity
GO:0000747 Process conjugation with cellular fusion
GO:0051039 Process positive regulation of transcription, meiotic

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_001022578 NP_596656

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

CAA18162   NP_596656   P36631   T40223  

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Kjaerulff S, et al. (2007) "Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1." Genes Dev. 21(3):347-359. PMID:17289922
  2. [ + ] Aslett M, et al. (2006) "Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%." Yeast. 23(13):913-919. PMID:17072883
  3. [ + ] Alvarez B, et al. (2006) "Fission yeast Tor2 promotes cell growth and represses cell differentiation." J Cell Sci. 119(Pt 21):4475-4485. PMID:17046992
  4. [ + ] Matsuyama A, et al. (2006) "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Nat Biotechnol. 24(7):841-847. PMID:16823372
  5. [ + ] Nakase Y, et al. (2006) "A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex." Genetics. 173(2):569-578. PMID:16624901
  6. [ + ] Kjaerulff S, et al. (2005) "Constitutive activation of the fission yeast pheromone-responsive pathway induces ectopic meiosis and reveals ste11 as a mitogen-activated protein kinase target." Mol Cell Biol. 25(5):2045-2059. PMID:15713656
  7. [ + ] Wood V, et al. (2002) "The genome sequence of Schizosaccharomyces pombe." Nature. 415(6874):871-880. PMID:11859360
  8. [ + ] Kitamura K, et al. (2001) "Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast." Dev Cell. 1(3):389-399. PMID:11702950
  9. [ + ] Shinozaki-Yabana S, et al. (2000) "Novel WD-repeat protein Mip1p facilitates function of the meiotic regulator Mei2p in fission yeast." Mol Cell Biol. 20(4):1234-1242. PMID:10648609
  10. [ + ] Kjaerulff S, et al. (1997) "Cell differentiation by interaction of two HMG-box proteins: Mat1-Mc activates M cell-specific genes in S.pombe by recruiting the ubiquitous transcription factor Ste11 to weak binding sites." EMBO J. 16(13):4021-4033. PMID:9233811
  11. [ + ] Li P, et al. (1996) "Molecular mimicry in development: identification of ste11+ as a substrate and mei3+ as a pseudosubstrate inhibitor of ran1+ kinase." Cell. 87(5):869-880. PMID:8945514
  12. [ + ] Kato T Jr, et al. (1996) "Stress signal, mediated by a Hog1-like MAP kinase, controls sexual development in fission yeast." FEBS Lett. 378(3):207-212. PMID:8557102
  13. [ + ] Sugimoto A, et al. (1991) "Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development." Genes Dev. 5(11):1990-1999. PMID:1657709
  14. [ + ] Sipiczki M, et al. (1988) "The role of sterility genes (ste and aff) in the initiation of sexual development in Schizosaccharomyces pombe." Mol Gen Genet. 213(2-3):529-534. PMID:3185514