abp1 | GeneID:2539971 | Schizosaccharomyces pombe

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 2539971 Official Symbol abp1
Locus SPBC1105.04c Gene Type protein-coding
Synonyms cbp1
Full Name N/A
Description CENP-B homolog
Chromosome N/A
Also Known As
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 2797

ID Symbol Protein Species
GeneID:8690 JRKL NP_003763.2 Homo sapiens
GeneID:77532 Jrkl XP_001472522.1 Mus musculus
GeneID:315417 Jrkl XP_235818.2 Rattus norvegicus
GeneID:476764 JRKL XP_533970.1 Canis lupus familiaris
GeneID:539736 JRKL XP_589056.1 Bos taurus
GeneID:1269486 AgaP_AGAP003894 XP_308124.2 Anopheles gambiae
GeneID:2539728 cbh2 NP_596738.1 Schizosaccharomyces pombe
GeneID:2539971 abp1 NP_596460.1 Schizosaccharomyces pombe
GeneID:2543290 cbh NP_594583.1 Schizosaccharomyces pombe

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0000780 Component condensed nuclear chromosome, centromeric region
GO:0000790 Component nuclear chromatin
GO:0005634 Component nucleus
GO:0019237 Function centromeric DNA binding
GO:0005515 Function protein binding
GO:0046983 Function protein dimerization activity
GO:0030702 Process chromatin silencing at centromere
GO:0007059 Process chromosome segregation
GO:0006270 Process DNA replication initiation
GO:0016570 Process histone modification

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_001022379 NP_596460

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

CAB50967   NP_596460   P49777   T39281  

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Cam HP, et al. (2008) "Host genome surveillance for retrotransposons by transposon-derived proteins." Nature. 451(7177):431-436. PMID:18094683
  2. [ + ] Aguilar-Arnal L, et al. (2008) "The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching." EMBO J. 27(7):1029-1038. PMID:18354497
  3. [ + ] Matsuyama A, et al. (2006) "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Nat Biotechnol. 24(7):841-847. PMID:16823372
  4. [ + ] Fedyanina OS, et al. (2006) "Chromosome segregation in fission yeast with mutations in the tubulin folding cofactor D." Curr Genet. 50(5):281-294. PMID:17004072
  5. [ + ] Aslett M, et al. (2006) "Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%." Yeast. 23(13):913-919. PMID:17072883
  6. [ + ] Locovei AM, et al. (2006) "The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast." Cell Div. 1():27. PMID:17112379
  7. [ + ] Taricani L, et al. (2002) "The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein." J Biol Chem. 277(12):10562-10572. PMID:11751918
  8. [ + ] Wood V, et al. (2002) "The genome sequence of Schizosaccharomyces pombe." Nature. 415(6874):871-880. PMID:11859360
  9. [ + ] Nakagawa H, et al. (2002) "Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications." Genes Dev. 16(14):1766-1778. PMID:12130537
  10. [ + ] Irelan JT, et al. (2001) "Functional redundancies, distinct localizations and interactions among three fission yeast homologs of centromere protein-B." Genetics. 157(3):1191-1203. PMID:11238404
  11. [ + ] Baum M, et al. (2000) "Fission yeast homologs of human CENP-B have redundant functions affecting cell growth and chromosome segregation." Mol Cell Biol. 20(8):2852-2864. PMID:10733588
  12. [ + ] Halverson D, et al. (1997) "A centromere DNA-binding protein from fission yeast affects chromosome segregation and has homology to human CENP-B." J Cell Biol. 136(3):487-500. PMID:9024682