alp8 | GeneID:2539047 | Schizosaccharomyces pombe

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 2539047 Official Symbol alp8
Locus SPCC1223.06 Gene Type protein-coding
Synonyms tea1
Full Name N/A
Description cell end marker Tea1
Chromosome N/A
Also Known As
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 117296

ID Symbol Protein Species
GeneID:819963 AT3G07720 NP_566316.1 Arabidopsis thaliana
GeneID:856563 KEL1 NP_012028.1 Saccharomyces cerevisiae
GeneID:2539047 alp8 NP_588351.1 Schizosaccharomyces pombe
GeneID:2682428 MGG_02875 XP_366799.1 Magnaporthe grisea
GeneID:2706788 NCU00622.1 XP_324802.1 Neurospora crassa
GeneID:4346503 Os09g0249000 NP_001062670.1 Oryza sativa
GeneID:4620089 AGOS_ADL149W NP_983947.1 Eremothecium gossypii

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0051285 Component cell cortex of cell tip
GO:0032153 Component cell division site
GO:0051286 Component cell tip
GO:0005875 Component microtubule associated complex
GO:0015630 Component microtubule cytoskeleton
GO:0031500 Component Tea1 cell-end complex
GO:0042802 Function identical protein binding
GO:0005515 Function protein binding
GO:0051519 Process activation of bipolar cell growth
GO:0042815 Process bipolar cell growth
GO:0034613 Process cellular protein localization
GO:0007163 Process establishment or maintenance of cell polarity
GO:0032465 Process regulation of cytokinesis

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_001023342 NP_588351

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]

Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

CAA20875   CAA73246   NP_588351   P87061   T40866  

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] La Carbona S, et al. (2006) "Spatial regulation of cytokinesis by the Kin1 and Pom1 kinases in fission yeast." Curr Genet. 50(6):377-391. PMID:16988828
  2. [ + ] Grallert A, et al. (2006) "S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner." Genes Dev. 20(17):2421-2436. PMID:16951255
  3. [ + ] Matsuyama A, et al. (2006) "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Nat Biotechnol. 24(7):841-847. PMID:16823372
  4. [ + ] Choi E, et al. (2006) "Function of rax2p in the polarized growth of fission yeast." Mol Cells. 22(2):146-153. PMID:17085965
  5. [ + ] Martin SG, et al. (2005) "Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity." Dev Cell. 8(4):479-491. PMID:15809031
  6. [ + ] Snaith HA, et al. (2005) "Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast." EMBO J. 24(21):3690-3699. PMID:16222337
  7. [ + ] Ge W, et al. (2005) "The novel fission yeast protein Pal1p interacts with Hip1-related Sla2p/End4p and is involved in cellular morphogenesis." Mol Biol Cell. 16(9):4124-4138. PMID:15975911
  8. [ + ] Tatebe H, et al. (2005) "Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe." Curr Biol. 15(11):1006-1015. PMID:15936270
  9. [ + ] Pardo M, et al. (2005) "The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast." J Cell Sci. 118(Pt 8):1705-1714. PMID:15797925
  10. [ + ] Castagnetti S, et al. (2005) "End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe." J Cell Sci. 118(Pt 9):1843-1850. PMID:15827087
  11. [ + ] Feierbach B, et al. (2004) "Regulation of a formin complex by the microtubule plus end protein tea1p." J Cell Biol. 165(5):697-707. PMID:15184402
  12. [ + ] Yang P, et al. (2003) "The novel Rho GTPase-activating protein family protein, Rga8, provides a potential link between Cdc42/p21-activated kinase and Rho signaling pathways in the fission yeast, Schizosaccharomyces pombe." J Biol Chem. 278(49):48821-48830. PMID:14506270
  13. [ + ] Kim H, et al. (2003) "The kelch repeat protein, Tea1, is a potential substrate target of the p21-activated kinase, Shk1, in the fission yeast, Schizosaccharomyces pombe." J Biol Chem. 278(32):30074-30082. PMID:12764130
  14. [ + ] Snaith HA, et al. (2003) "Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips." Nature. 423(6940):647-651. PMID:12789340
  15. [ + ] Niccoli T, et al. (2003) "Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe." Yeast. 20(16):1349-1358. PMID:14663827
  16. [ + ] Papadaki P, et al. (2002) "Two ras pathways in fission yeast are differentially regulated by two ras guanine nucleotide exchange factors." Mol Cell Biol. 22(13):4598-4606. PMID:12052869
  17. [ + ] Behrens R, et al. (2002) "Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton." J Cell Biol. 157(5):783-793. PMID:12034771
  18. [ + ] Qyang Y, et al. (2002) "The p21-activated kinase, Shk1, is required for proper regulation of microtubule dynamics in the fission yeast, Schizosaccharomyces pombe." Mol Microbiol. 44(2):325-334. PMID:11972773
  19. [ + ] Niccoli T, et al. (2002) "Different mechanisms of cell polarisation in vegetative and shmooing growth in fission yeast." J Cell Sci. 115(Pt 8):1651-1662. PMID:11950884
  20. [ + ] Wood V, et al. (2002) "The genome sequence of Schizosaccharomyces pombe." Nature. 415(6874):871-880. PMID:11859360
  21. [ + ] Glynn JM, et al. (2001) "Role of bud6p and tea1p in the interaction between actin and microtubules for the establishment of cell polarity in fission yeast." Curr Biol. 11(11):836-845. PMID:11516644
  22. [ + ] Bahler J, et al. (1998) "Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis." Genes Dev. 12(9):1356-1370. PMID:9573052
  23. [ + ] Hirata D, et al. (1998) "Genes that cause aberrant cell morphology by overexpression in fission yeast: a role of a small GTP-binding protein Rho2 in cell morphogenesis." J Cell Sci. 111 ( Pt 2)():149-159. PMID:9405296
  24. [ + ] Arellano M, et al. (1997) "Localisation of the Schizosaccharomyces pombe rho1p GTPase and its involvement in the organisation of the actin cytoskeleton." J Cell Sci. 110 ( Pt 20)():2547-2555. PMID:9372443
  25. [ + ] Mata J, et al. (1997) "tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell." Cell. 89(6):939-949. PMID:9200612