aap-1 | GeneID:172141 | Caenorhabditis elegans

Gene Summary

[ - ] NCBI Entrez Gene

Gene ID 172141 Official Symbol aap-1
Locus Y110A7A.10 Gene Type protein-coding
Full Name N/A
Description phosphoinositide kinase AdAPter subunit
Chromosome N/A
Also Known As phosphoinositide kinase AdAPter subunit family member (aap-1)
Summary N/A

Orthologs and Paralogs

[ - ] Homologs - NCBI's HomoloGene Group: 7889

ID Symbol Protein Species
GeneID:5295 PIK3R1 NP_852664.1 Homo sapiens
GeneID:18708 Pik3r1 NP_001070963.1 Mus musculus
GeneID:25513 Pik3r1 NP_037137.1 Rattus norvegicus
GeneID:172141 aap-1 NP_491522.1 Caenorhabditis elegans
GeneID:282307 PIK3R1 NP_777000.1 Bos taurus
GeneID:427171 PIK3R1 XP_424759.1 Gallus gallus
GeneID:461836 PIK3R1 XP_517729.2 Pan troglodytes
GeneID:487235 PIK3R1 XP_850341.1 Canis lupus familiaris
GeneID:557176 LOC557176 XP_683819.2 Danio rerio

Gene Classification

[ - ] Gene Ontology

IDCategoryGO Term
GO:0005942 Component phosphoinositide 3-kinase complex
GO:0035014 Function phosphoinositide 3-kinase regulator activity
GO:0005515 Function protein binding
GO:0040024 Process dauer larval development
GO:0008340 Process determination of adult life span
GO:0008286 Process insulin receptor signaling pathway

RefSeq Isoforms

[ - ] RefSeq Annotation and UniProt Database

No. RefSeq RNA RefSeq Protein UniProt Equivalent
1 NM_059121 NP_491522

Transcript Sequences

[ - ] Transcript Accession Number Cloud [ GenBank ]


Protein Sequences

[ - ] Protein Accession Number Cloud [ GenPept ]

Gene Interactions

[ - ] BioGRID Gene Product Interaction Database

Symbol Interaction Binary Experiment Source
atp-2 aap-1 / atp-2 Two-hybrid Li S (2004)
mog-5 aap-1 / mog-5 Two-hybrid Li S (2004)
N/A aap-1 / N/A Two-hybrid Li S (2004)
pal-1 aap-1 / pal-1 Two-hybrid Li S (2004)
p-glycoprotein aap-1 / p-glycoprotein Two-hybrid Li S (2004)
rpl-3 aap-1 / rpl-3 Two-hybrid Li S (2004)
tsp-10 aap-1 / tsp-10 Two-hybrid Li S (2004)
Y45G5AL.1 aap-1 / Y45G5AL.1 Two-hybrid Li S (2004)

Transcript Cluster

[ - ] NCBI's UniGene

Selected Publications

[ - ] Gene-related publications indexed at PubMed

  1. [ + ] Li S, et al. (2004) "A map of the interactome network of the metazoan C. elegans." Science. 303(5657):540-543. PMID:14704431
  2. [ + ] Mulder NJ, et al. (2003) "The InterPro Database, 2003 brings increased coverage and new features." Nucleic Acids Res. 31(1):315-318. PMID:12520011
  3. [ + ] Camon E, et al. (2003) "The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro." Genome Res. 13(4):662-672. PMID:12654719
  4. [ + ] Wolkow CA, et al. (2002) "Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway." J Biol Chem. 277(51):49591-49597. PMID:12393910